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Contents
 
Introduction
Help Videos
Reference Guide
Getting Started
Protein Structure
Molecular Graphics
Slides & ActiveICM
Sequences & Alignments
Protein Modeling
 Homology Modeling
 Loop Modeling
 Design Loop
 Graft Loop
 Loop Preferred Residues
 Find PDB Loop Segment
 Regul
 Refine SC
 Make Disulfide Bond
 Make a Mutation
 Modify Amino Acid
 Mutation - Protein Binding
 Mutation - Protein Stability
 Protein Peptide
 Protein Ligand
 Disulfide Bond
 Sculpting
 Sample Protein
 Sample Peptide
 Molecular Mechanics
Cheminformatics
Learn and Predict
Docking
Virtual Screening
MolScreen
3D Ligand Editor
Tables and Plots
Local Databases
ICM-Scarab
KNIME
Tutorials
FAQs
 
Index
PrevICM User's Guide
9.10 Making a Mutation
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Available in the following product(s): ICM-Pro

How to Mutate or Modify an Amino Acid Residue
In order to make a mutation the molecule needs to be an ICM Object. Right click on the amino acid residue you wish to mutate and choose Advanced and then select one of the mutation options. For the extended list of unusual amino acids the codes in the drop down box refer to the codes at the PDB Ligand Expo website here http://ligand-expo.rcsb.org/


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