Browse and save proteins, chemicals, sequences, alignments, and much more...
Ligand-Receptor Interactions
Generate pocket surfaces colored by binding property and display hydrogen bonds.
View sequence alignments
Display 3D interactive molecules on the web
Embed fully interactive 3D molecules into web browsers such as Safari, IE, Google Chrome and Firefox.
Publish with ActiveICM and ICM-Browser
The PLoS One journal accepts fully interactive 3D documents in Active ICM.
Publish with ActiveICM and ICM-Browser
PloS Biology and Molecular and Cellular Proteomics journals also accept ActiveICM format.
Direct link to Protein and Sequence Databases
Powerful protein databank search capabilities and one click load and display options.
Superimpose multiple proteins
Display 3D interactive molecules in PowerPoint
Embed fully interactive 3D molecules into Windows Powerpoint.
Display 3D interactive molecules in PowerPoint
Embed multiple fully interactive 3D molecules into Windows Powerpoint.
Background
ICM-Browser provides a biologist or a chemist with direct access to the treasures of structural biology and protein families.It
reads a variety of file formats directly from the database web-sites including: PDB, chemical, electron density maps, sequence and alignment files. ICM-Browser provides a rich professional molecular graphics
environment with powerful representations of proteins, DNA and RNA, and multiple sequence alignments.
Fall 2010 New Features! You can now save fully interactive 3D files to display on the web or in PowerPoint. You can also add and optimize hyrogens to PDB files, display hydrogen bonds, and display
transparent ligand binding pocket property surfaces as well as other molecule sufaces.
Who should use the ICM-Browser?
The ICM-Browser is ideal for:
Scientists who wish to communicate their data via fully-interactive and annotated 3D slides via PowerPoint or on the Web.
A biology student or researcher to look at biological structures from the PDB as well as sequences and alignments.
A chemist who wants to view chemical structures and ligand-receptor interactions.
A researcher who wants to look at annotated models or alignments built by a modeler colleague who uses other ICM tools.
New Fully-Interactive 3D Publishing and Display Features Added to ICM-Browser
Build and Save Fully-Annotated and Interactive 3D Files and Display them in PowerPoint and on the Web (Patent Pending). Save
multiple annotated and animated fully-interactive 3D views and slides of your molecules to display in PowerPoint and on the web using the free ActiveICM plugin. Automatically memorize viewpoints, slides,
animations, and transitions all stored within a single file. Share the file with your colleagues via Microsoft products, web browsers or in the free ICM-Browser itself. More...
Display Transparent Ligand Binding Pocket Surfaces. Display ligand binding pocket surface colored by binding property. White=neutral
surface, Green=hydrophobic surface, Red=hydrogen bonding acceptor potential, and Blue=hydrogen bond donor potential. In order to display the property surface the PDB file needs to be converted into an ICM object.
Add and Optimize Hydrogens to a PDB file and Display Hydrogen
Bonds. You can now convert a PDB file into an ICM
object which is a full-atom representation of the molecule. The hydrogen atoms can be optimized to identify their energetically optimal positions. Once hydrogens are added to the molecule hydrogen bonds can be
displayed.The coloring of the hydrogen bonds are red (strong - thick spheres) to blue (weak - thin spheres).
Generate and Display Surfaces. Generate and display molecule surfaces (meshes). Display in dot, wire, solid
rugged, solid smooth or smooth transparent representation.
ICM-Browser Features
Load and Display Many
Molecular Structure and Sequence File Types. ICM-Browser supports many different file types for protein structures, chemicals, sequences,
alignments and other objects. More...
Combined Views, Animations and Slides (Patent Pending). Create ICM Molecular documents and
presentations, memorize viewpoints and slides, automatically memorize animations and transitions stored within a single file. More...
Publication Quality Molecular Graphics. Utilize a full and robust array of graphics tools all accessible from a GUI interface. Display your molecules in wire, CPK, ball & stick, worm, ribbon, accessible surface, transparent molecular surface, perspective, depth cueing, smooth and rugged solid surfaces. Use both hardware and side-by-side stereo. More...
Powerful PDB Search Engine. ICM-Browser gives you direct access to the Protein Structure Databank
(PDB). Type in a search string and a table of structures matching your search will be diplayed. Double click on the table and the structure will be downloaded and displayed in the graphical user interface.
More...
Save Rich Molecular Graphics Images.
Use ICM-Browser to create high resolution images. The ICM software is well renowned for producing high-quality images which have been used in scientific publications, journal covers as well as videos and TV commercials.
More...
View and Make High Resolution Images of
Alignments Alignments can be directly linked to the displayed 3D structure. Alignments can be annotated, boxed and colored, the alignment can be exported as a high-quality image for publication.
More...
Superimpose Protein Structures. Select the region of
the molecules you wish to superimpose and then with one click the molecules will superimpose. More...
Measure Distances and Angles. Measure distances between atoms, calculate planar and torsion angles. More...
The next step up from ICM-Browser is the low cost ICM-Browser-Pro. Create your own annotated structure files with the ICM-Browser upgrade called ICM-Browser-Pro. ICM-Browser-Pro allows you to start from external files or from scratch and create and save your own project file (called .icb). It also has some extended features not included in the ICM-Browser.
Note: If the ICM Browser Software is licensed to you free of charge, it does not include technical support.Bug reports and reports of errors or other problems are appreciated and should be sent to support@molsoft.com.
