| Mar 8 2010 |
Background
The ICM Suite of Software provides an easy to use general environment for a biologist or
chemist who is curious about protein structure. In just a few seconds you can
browse hundreds of structures of interest, analyze and
visualize sequences, alignments and binding sites. Also you can perform molecular modeling, fully-flexible ligand and receptor docking, virtual ligand screening, chemical similarity searching,
chemical clustering and much more...
This book describes how to use the program via the Graphical User Interface (GUI)
without the knowledge of the commands and functions running
through your terminal window. After reading this book you may read the
full ICM Language Reference Manual (www.molsoft.com/man) for the dying breed of command line
users and occasional programmers. This is a separate document which is
provided with a full ICM distribution or can be obtained from Molsoft in a printed form.
ICM is constantly updated with new features and so it is always a good idea to keep an eye on the release notes. Most of the things you will read in this manual are sort of natural or can be figured out by common sense and trial-and-error. However, if you like to read a "structured" description of the material, go ahead and read this.Since this book is intended for basically anyone who is even remotely interested in molecules, some basic knowledge of biology and chemistry is implied. Do not try to find definitions of "atom" or "sequence" here, but most terms beyond that will be explained. A keyword search of this manual is available on the online version which is located at (www.molsoft.com/gui). This book covers the graphical user interface only. For detailed information regarding ICM programming please consult the separate ICM language reference guide (www.molsoft.com/man).If you want to have a more hands-on introduction to ICM you are always more than welcome to join us at one of our ICM workshops which are held periodically throughout the year (click here for training information).
ICM Specifications and RecomendationsMinimum specification for Windows, Mac, SGI and Linux: 55 Mb of disk space and 256Mb or more of memory. 512Mb of memory is good enough. Our databases such as XPDB require another 1Gb of disk space. The Graphic card should have Hardware OpenGL acceleration and 64Mb or more memory. (128Mb or more is recommended) We recommend NVIDIA (http://www.nvidia.com) brand.
If you need Stereo Glasses we can recommend CrystalEyes: http://reald-corporate.com/scientific/crystaleyes.asp
Requesting an ICM license and InstallationTo obtain an ICM license (either trial of full) please follow these steps: You can choose either a nodelocked or floating license. A nodelocked license will be for a single machine whereas a floating license will be placed on a server and can be accessed from any machine connected to that server.
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